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Tenormin Comprimé

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Disopyramide is a Type I antiarrhythmic drug with potent negative inotropic Priligy Par Mail chronotropic effects.

Disopyramide has been associated with severe bradycardia, Tenormin Comprimé, asystole and heart failure when administered with beta blockers.

Tenormin Comprimé

Amiodarone is an antiarrhythmic agent with negative chronotropic properties that may be additive to those seen with beta blockers. Beta blockers may exacerbate the rebound hypertension which can follow the Tenormin Comprimé of clonidine.

If the two drugs are coadministered, the beta blocker should be withdrawn several days before the gradual withdrawal of clonidine.

Tenormin Comprimé

If replacing clonidine by beta-blocker therapy, the introduction of beta blockers should be delayed for several days after clonidine administration has stopped, Tenormin Comprimé. Concomitant use of prostaglandin synthase inhibiting drugs, eg, indomethacinmay decrease the hypotensive effects of beta blockers. Information on concurrent usage of atenolol and aspirin is limited. While taking beta blockers, patients with a history of anaphylactic reaction to a variety of allergens may have a more severe reaction on repeated challenge, either accidental, diagnostic or Tenormin Comprimé.

Such patients may be unresponsive to the usual doses of epinephrine used to treat the allergic reaction. Both digitalis glycosides and beta-blockers slow atrioventricular conduction and decrease heart rate. Concomitant use can increase the risk of bradycardia. Warnings WARNINGS Cardiac Failure Sympathetic stimulation is necessary in supporting circulatory function in congestive heart failureand Tenormin Comprimé blockade carries the potential hazard of further depressing myocardial contractility and precipitating more Tenormin Comprimé failure.

In patients with acute myocardial infarctioncardiac failure which is not promptly and effectively controlled by 80 mg of intravenous furosemide or equivalent therapy is a contraindication to beta-blocker treatment, Tenormin Comprimé.

In Patients Without A History Of Cardiac Failure Continued depression of the myocardium with beta-blocking agents over a period of time can, in some cases, lead to cardiac failure. At the first sign or symptom of impending cardiac failure, Tenormin Comprimé should be treated appropriately according to Tenormin Comprimé recommended guidelines, and the response observed closely.

Severe exacerbation of angina and Tenormin Comprimé occurrence of myocardial infarction and ventricular arrhythmias have been reported in angina patients Tenormin Comprimé the abrupt discontinuation of therapy with beta blockers. The last two complications may occur with or without preceding exacerbation of the angina pectoris.

As with other beta blockers, when discontinuation of TENORMIN is planned, the patients should be carefully observed and advised to limit physical activity to a minimum.

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Because coronary artery disease is common and may be unrecognized, it may be prudent not to discontinue TENORMIN therapy abruptly even Tenormin Comprimé patients treated only for hypertension. Concomitant Use Of Calcium Channel Blockers Bradycardia and heart block can occur and the left ventricular end diastolic pressure can rise when beta-blockers are administered with verapamil or diltiazem.

Patients with preexisting conduction abnormalities or left ventricular dysfunction are particularly susceptible. Because of its relative beta1 selectivity, however, Tenormin Comprimé, TENORMIN may be used with caution in patients with bronchospastic disease who do not respond to, Tenormin Comprimé, or cannot tolerate, other antihypertensive treatment.

Since beta1 selectivity is Tenormin Comprimé absolute, the lowest possible dose of TENORMIN Tenormin Comprimé be used with therapy initiated at 50 mg and a beta2-stimulating agent bronchodilator should be made available.

If dosage must be Tenormin Comprimé, dividing the Tenormin Comprimé should be considered in order to achieve lower peak blood levels. Major Surgery Chronically administered beta-blocking therapy should not be routinely withdrawn prior to major surgery, however the impaired ability of the heart to respond to reflex adrenergic stimuli may augment the risks of general Tenormin Comprimé and surgical procedures.

Beta blockers may mask tachycardia occurring with hypoglycemiabut other manifestations such as dizziness and sweating may not be significantly affected. At recommended doses TENORMIN does not potentiate insulin -induced hypoglycemia and, Tenormin Comprimé, unlike nonselective beta blockers, does not delay recovery of blood Tenormin Comprimé to normal levels.

Thyrotoxicosis Beta-adrenergic blockade may mask certain clinical signs eg, Tenormin Comprimé, tachycardia of hyperthyroidism. Abrupt withdrawal of beta blockade might precipitate a thyroid storm ; therefore, patients suspected of developing thyrotoxicosis from whom TENORMIN therapy is to be withdrawn should be monitored closely.

Pregnancy And Fetal Injury Atenolol can cause fetal harm when administered to a pregnant woman, Tenormin Comprimé. Atenolol crosses the placental barrier and appears in cord blood. Administration of atenolol, starting in the second trimester of pregnancy, has been associated with the birth of infants that are small for gestational age.

No studies have been performed on the use of atenolol in the first trimester and the possibility of fetal injury cannot be excluded. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus.

Impaired Renal Function The drug should be used with caution in patients with impaired renal function. No evidence of a mutagenic potential of atenolol was uncovered in the dominant lethal test mousein vivo cytogenetics test Chinese hamster or Ames test S typhimurium.

What is atenolol?

Nursing Mothers Atenolol is excreted in human breast milk at a ratio of 1. Clinically significant bradycardia has been reported in breast-fed infants. Premature infants, or infants with impaired renal function, may be more Tenormin Comprimé to develop adverse effects.

Pediatric Use Safety and effectiveness in pediatric patients have not been established. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.

Tenormin Comprimé general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting greater frequency of decreased hepatic, renal, or cardiac function, Tenormin Comprimé, and of concomitant disease Tenormin Comprimé other drug therapy.

Evaluation of patients with hypertension or myocardial infarction should always Tenormin Comprimé assessment of renal function.

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One death was reported in a man who may have taken as Tenormin Comprimé as 10 g acutely. Treatment of overdose should be directed to the removal of any unabsorbed drug by induced emesisTenormin Comprimé, gastric lavage, or administration of activated charcoal. Other treatment modalities should be employed at the physician’s discretion and may include: If there is no response to vagal blockade, give isoproterenol cautiously.

In refractory cases, a transvenous cardiac pacemaker may be indicated.

Important information

Isoproterenol or transvenous cardiac pacemaker. Digitalize the patient and administer a diuretic. Glucagon has been reported to be useful. Vasopressors such as dopamine or norepinephrine levarterenol, Tenormin Comprimé. Monitor blood pressure continuously. Based on the severity of Tenormin Comprimé, management may require intensive support care and facilities for applying cardiac and respiratory support. TENORMIN is contraindicated in those patients with a history of hypersensitivity to the atenolol or any of the drug product’s components.

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